Overexpression of Optic Atrophy Type 1 Protects Retinal Ganglion Cells and Upregulates Parkin Expression in Experimental Glaucoma
Glaucoma is a neurodegenerative disease that features progressive loss of retinal ganglion cells (RGCs).Increasing evidences have revealed that impaired mitochondrial dynamics occurs early in neurodegenerative diseases.Optic Atrophy Type 1 (OPA1), a mitochondrial fusion protein, has recently been suggested to be a mitophagic factor.Our previous stu